Seminars

UCI Spatial Omics Symposium

Tuesday 04/23/2024

1:00 to 6:00 p.m.

Sue and Bill Gross Stem Cell Research Center - Thorp Conference Center (4001)

The Genomics Research and Technology Hub and Precision Health are excited to bring you “UCI Spatial Omics”, an afternoon of recent progress in spatial omics research. Please join us for lively discussions of progress, challenges, and future applications of these technologies

Agenda

Time	Presenter	Topic
1:00 – 1:15 PM	Michael Hicks	Spatial transcriptomics combined with CRISPR/Cas9 to interrogate cell-niche interactions
1:15 – 1:30 PM	Matt Rose	Customizing the slide-seq platform
1:30 – 1:45 PM	Matt Blurton Jones	Peripherally-derived human monocytes induce a chronic proinflammatory state within the brains of chimeric mice
1:45 – 2:00 PM	Yingzi Liu	Spatial transcriptomics genomics in skin using the 10x Genomics Visium platform
2:00 – 2:10 PM	Q&A Session 1	Q&A
2:10 – 2:30 PM	Break
2:30 – 2:45 PM	Bogi Anderson	Skin spatial transcriptomic on the Resolve Molecular Cartography platform
2:45 – 3:00 PM	Madi Tetzlaff	Spatial transcriptomics of the paraventricular thalamus in mouse and human: considering a possible node of enduring emotional memory
3:00 – 3:15 PM	Zhiqun Tan	Application of Vizgen MERFISH to brain circuitry discovery
3:15 – 3:30 PM	Vivek Swarup	Spatial transcriptomics approaches to neuroscience: opportunities and challenges
3:30 – 3:45 PM	Kim Green	Nanostring CosMx for single cell spatial transcriptomic and proteomic exploration of the mouse brain
3:45 – 4:00 PM	Devon Lawson	Exploring breast cancer development using 10X Genomics Visium and Xenium platforms
4:00 – 4:15 PM	Mara Burns	Spatiotemporal transcriptomics analysis of the R6/2 HD mouse brain reveals distinct and early molecular signatures
4:15 – 4:30 PM	Q&A Session 2	Q&A
4:30 – 4:45 PM	Vanessa Scarfone	Spatial proteomics using imaging mass cytometry
4:45 – 5:00 PM	Felix Grun	Spatial metabolomics, lipidomics and peptidomics by IMS
5:00 – 5:15 PM	Q&A Session 3	Q&A
5:30 – 6:00 PM	Reception

Genetics, Biomedical Computing and Genomics Seminar – Novel Approaches to Doing Whole Genome Editing

Tuesday 03/05/2024

10:00 to 11:00 a.m

Webinar

“Eye on Genome Editing”

Krzysztof Palczewski, PhD, is a UCI Distinguished Professor and Donald Bren Professor in the Departments of Ophthalmology and Physiology and Biophysics and holds the Irving H. Leopold Chair in Ophthalmology in the Gavin Herbert Eye Institute, School of Medicine, UCI.

Professor Palczewski received his MS and PhD degrees from University of Wroclaw and Technical University of Wroclaw, respectively (Poland). He has moved up the professorial ranks at several institutions, including U of Washington in Seattle, and Case Western Reserve. He was recruited to UCI in 2018. Among other accomplishments in the short time Professor Palczewski has been at UCI, he has recruited additional outstanding vision researchers, and founded the Center for Translational Vision Research which was recently awarded a NIH P30 program grant. He is a recipient of the prestigious Prize of the Foundation for Polish Science and is a member of the US National Academy of Medicine and member of the National Academy of Sciences. Professor Palczewski is known for characterizing crystal structures of native and activated forms of the G protein-coupled receptor, rhodopsin, involved in eyesight. His group has probed the inner structure of the eye using 2 photon microscopy. His research includes understanding hereditary diseases of the eye with the goal of tailored therapeutics. He will be speaking today about recent developments in CRISPR editing.

“Rapid Functional Testing of Human Noncoding Disease Variants in Live Mice”

Ethan Hollingsworth is an MD PhD student in his third year in the Evgeny Kvon Lab, Developmental and Cell Biology. Ethan received his B.S. in Zoology and Neuroscience from Miami University of Ohio. His work is focused on understanding how non-coding mutations cause human disease.

A Genetics Biomedical Computing & Genomics Seminar

Scalable Computing and Storage at UCI? What’s available. What’s new.

Tuesday 10/03/2023

Phil Papadopoulos, PhD, Director of the Research Cyber Infrastructure Center

Presentation

Overview of RCIC Resources. Some New Things. And BACKUP your STUFF

PacBio Long Read Sequencing Seminar

Monday 02/05/2024

12:00pm - 2:00pm

UCI, Sprague Hall, Room 105

Join us to celebrate the arrival of the Revio, PacBio’s new high throughput long read sequencer, at the Genomics Research and Technology Hub (GRT Hub) at UCI. The seminar is free, but registration is required..

Copy of Presentation (PDF)

Agenda

12:00pm

Introduction to highly accurate long-read sequencing (HiFi), Chris Black, PacBio
Exploring key and emerging applications of HiFi sequencing, Chris Black, PacBio
Announcement of the SMRT Grant opportunity at the GRT Hub, Alex Westman, PacBio
Long-read sequencing services at the Genomics Research and Technology Hub (GRT Hub), Melanie Oakes, UCI

1:00pm